Their attacking duo, Kevin Denkey and Evander, have been on fire this season, combining for 25 goals, and will be crucial up front.
After a poor showing against Columbus, Miles Robinson may be dropped, with Alvas Powell expected to take his place in defense.
Inter Miami are also facing injury troubles, missing key players such as Allen Obando, David Ruiz, Drake Callender, Gonzalo Lujan, Ian Fray, Noah Allen, and Yannick Bright. Additionally, Marcelo Weigandt is doubtful after picking up an injury last week, possibly making way for Ryan Sailor at right-back.
Up front, there’s no question that Lionel Messi will lead the attack alongside Luis Suarez, while Tadeo Allende and Telasco Segovia are expected to occupy the flanks.
Predicted Lineups
FC Cincinnati (3-5-2):
Celentano; Powell, Miazga, Engel; Yedlin, Anunga, Evander, Bucha, Orellano; Kamara, Denkey
Inter Miami (4-4-2):
Ustari; Sailor, Falcon, Martinez, Alba; Allende, Cremaschi, Busquets, Segovia; Messi, Suarez